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An aberration in chromosome structure resulting from an error in meiosis or from mutagens; specifically, reattachment of a chromosomal fragment to the chromosome from which the fragment originated, but in a reverse orientation.
inversion
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A dense object lying along the inside of the nuclear envelope in female mammalian cells, representing an inactivated X chromosome.
barr body
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(1) The conversion of a normal animal cell to a cancerous cell. (2) A change in genotype and phenotype due to the assimilation of external DNA by a cell.
transformation
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A virus that infects bacteria; also called a phage. See phage.
bacteriophage
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The form of native DNA, referring to its two adjacent polynucleotide strands wound into a spiral shape.
double helix
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Sites where the replication of a DNA molecule begins.
origins replication
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An enzyme that links together the growing chain of ribonucleotides during transcription.
RNA polymerase
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The new continuous complementary DNA strand synthesized along the template strand in the mandatory 5' 3' direction.
leading strand
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A discontinuously synthesized DNA strand that elongates in a direction away from the replication fork.
lagging strand
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A linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 39 end of a new DNA fragment to the 59 end of a growing chain.
DNA ligase
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