Which of the following is the correct sequence for an altered protein that is secreted from the cell?

  1. smooth endoplasmic reticulum - plasma membrane - Golgi apparatus - ribosome

  2. Golgi apparatus - ribosome - plasma membrane

  3. nucleus - smooth endoplasmic reticulum - Golgi apparatus

  4. rough endoplasmic reticulum - Golgi apparatus - plasma membrane

  5. Golgi apparatus - smooth endoplasmic reticulum - plasma membrane



The endomembrane system work together to carry out the synthesis and movement of materials throughout and out of the cell. In the sequences provided, materials such as proteins would move from the rough endoplasmic reticulum where a protein would be synthesized and then sent to the Golgi for modification and packaging for export then from the cell via the plasma membrane.